Collagen Synthesis

  • Reduced hydroxylation of proline and lysine due to Vit C deficiency  => SCURVY
  • Gene mutations of collagen (usually type I & III) and lysine hydroxilase => EHLERS DANLOS
  • Gene mutations of gene ATP7A results in Copper deficiency, reducing the activity of lysil oxidase => MENKES DISEASE (or Copper transport disease, or Kinky Hair Disease)
  1. usmle1mikmonics reblogged this from mynotes4usmle and added:
    my crazy personal mnemonic for collagen synthesis and defects: Collagen Synthesis Colling For All Sinners and...
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  3. diseasesinthreewords reblogged this from mynotes4usmle and added:
    Excelente resumen …
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